1. Isoflavone Benefits
Whether itâs tofu or soy milk, there are certain components that soy foods have in common. Called isoflavones, theyâre a unique class of phytochemicals (disease-fighting plant compounds). Isoflavones actually function as a weak form of the hormone estrogen and thatâs where their health benefits come in. The stars amongst these compounds are genistein and daidzein. Theyâve been attributed with reducing the risk of heart disease and certain types of cancers. Not only do soy foods contain isoflavones, but theyâre also rich in omega-3 fatty acids, fiber, and vitamins and minerals like calcium and iron.
2. Genistein and CFTR
Itâs believed that cystic fibrosis (CF) is caused by a mutation in a special protein called the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a chloride channel, meaning it functions to transfer the chloride ion across cell membranes. This mutation then leads to the chronic obstructive lung disease and pancreatic insufficiency that characterizes CF. Recent research has suggested that the genistein component of soy foods may help âactivateâ the CFTR in certain patients and restore more normal function.
3. Diabetes in Cystic Fibrosis
As cystic fibrosis patients grow older, the potential for additional complications increases. One of these is cystic fibrosis-related diabetes, or CFRD. Almost one-third of adult CF patients may develop this complication. CFRD is linked to both a deficiency of the insulin hormone and an impaired ability to metabolize glucose. It seems that the isoflavones in soy can actually improve the body's ability to process glucose. They appear to trigger certain pathways that regulate our metabolism.
4. A Complete Protein
One of the main benefits of soy foods in CF comes simply from its high protein content. Itâs a unique plant protein because itâs completeâit has all of the amino acids that are essential for our bodies. CF patients are at very high risk for malnutrition due to both malabsorption and inadequate protein and calorie intake. Patients that are already falling behind in terms of growth may require as much as five times the daily protein as a healthy child. Incorporating soy foods like tofu and soy milk into the diet may help increase overall protein intake and improve nutrition status.
5. Be Careful
Soy foods offer a number of health benefits, but they're also one of the most common allergenic foods. An allergy to soy typically first presents after an infant is started on a soy-based formula. Because food allergies are relatively common in CF patients, it's important that parents be aware of symptoms when introducing new foods. These may include hives, swelling of the lips, face, tongue, or throat, and/or difficulty breathing.
