Effects of Omeprazole

Effects of Omeprazole
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Omeprazole, also known by the brand name Prilosec, is a medication that is used to treat gastroesophageal reflux disease (GERD), erosive esophagitis, heartburn, and H. pylori induced gastric ulcers. Omeprazole belongs to the class of drugs known as proton pump inhibitors (PPIs), which work by decreasing the production of stomach acid. Proton pump inhibitors such as omeprazole are primarily intended for short-term treatment though many people take it for years. This drug is well-tolerated in that most people do not experience side effects.

Headache, Dizziness, Respiratory Tract Infections

Although most individuals do not experience adverse reactions to this medicine, eMedTV states that there were several commonly reported side effects that occurred in 1 to 7 percent of the participants. These common effects included headaches, dizziness and upper respiratory tract infections.

Gastrointestinal Problems

This medication affects the amount of stomach acid that is produced. Therefore, it may take some time for the body to adjust to the lower levels of acid. This can result in experiencing stomachaches, excessive gas, nausea with or without vomiting, and constipation. Diarrhea is another possible gastrointestinal effect that can lead to dehydration; thus, it is important to drink plenty of fluids in order to prevent becoming dehydrated. If any of these symptoms continue or get worse, call your doctor so that adjustments can be made.

Musculoskeletal Pain

According to Drugs.com, musculoskeletal side effects have been associated with this drug that include back pain, leg pain, and pain in the joints as well as muscle cramps. A more serious adverse reaction is the development of a nonspecific form of polyarthritis; fortunately, this effect tends to resolve itself after omeprazole is discontinued. Also, there is a severe association between long-term high doses of omeprazole and hip fractures. This major effect appears not to be specific solely to this medication, but rather, there is an increased risk for fractured hips for those who take long-term high dose PPI-type medications. Speak to your doctor if you have been on omeprazole for a considerable length of time.

References

Article reviewed by Libby Swope Wiersema Last updated on: Apr 1, 2010

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