Diphenhydramine is an antihistamine medication. It is used for the treatment of hay fever, allergies or the common cold. Diphenhydramine may also be used as a sleep aid. This medicine should not be given to newborn infants or women who are breast feeding, states PDR Health. You can obtain diphenhydramine over the counter in pill, liquid and chewable tablet form.
Nausea and Constipation
You may experience nausea and constipation while taking diphenhydramine. These side effects may lessen over time as your body adjusts to the medication. Avoiding spicy and fried foods and choosing a bland diet may help abate nausea. Ginger and peppermint tea may relieve mild nausea. Constipation can also occur while taking diphenhydramine. Eating a diet rich in fruits and vegetables with additional fiber and water intake may alleviate constipation. If dietary changes are unsuccessful, an over-the-counter stool softener such as Colace may be helpful.
Lightheadedness, Fainting and Hallucinations
Lightheadedness and fainting are possible side effects of diphenhydramine. Hallucinations (seeing things that are not really there) may occur while taking diphenhydramine, reports PDR Health. Use caution while driving or operating hazardous machinery until you know how this medication will affect you. If these side effects become severe, contact your doctor prior to taking another dose of diphenhydramine.
Fatigue and Sleepiness
According to Drugs.com, fatigue and sleepiness can occur while taking diphenhydramine. You may feel more tired and sleepy than usual throughout the day. If you are using diphenhydramine at nighttime as a sleep aid, you may experience increased fatigue and sleepiness throughout the following day. Lowering your dosage may help alleviate fatigue and sleepiness. Get enough sleep nightly and take a mid-day nap if possible to avoid feeling sluggish. If these effects begin to impact your daily lifestyle, consider switching to an antihistamine that contains a non-drowsy formula.



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