Clindamycin is a prescription drug that's been in use for more than four decades. This medication falls in the class of lincomycin antibiotics, which inhibit or stop bacterial growth, the National Institutes of Health (NIH) says. Clindamycin may be taken orally to treat infections systemically, but it can also be applied topically as well. Topical clindamycin is most frequently used to keep acne under control.
Oral Clindamycin
Clindamycin taken orally resolves infections of the skin, lungs, blood, female reproductive system and other organs, the NIH says. It may also be used along with other medications to treat anthrax, malaria, ear infections and toxoplasmosis. Those at risk for developing an infection of the heart valves may also take clindamycin as a preventive treatment during or after dental procedures. Clindamycin is taken in capsule or liquid form, usually three to four times daily, depending on the nature of the infection.
Proper Use
Clindamycin works best when there is a consistent amount in the bloodstream, says the Mayo Clinic, which advises that daily dosages be spaced out evenly and none skipped. Take the medication with 8 oz. of water or a meal to reduce risk of esophageal irritation. Clindamycin must be taken for the full course of treatment recommended by your doctor, even if symptoms of infection begin to subside. Most common side effects associated with the medication are diarrhea, stomach pain, nausea and vomiting. Contact your doctor if side effects are severe, or if you notice less common adverse effects, such as sore throat, rash, itching, fever or any unusual bleeding or bruising.
Topical Clindamycin
When applied to the skin, clindamycin reduces the population of P. acnes bacteria that cause inflammation, the NIH says. Preparations include foam, gel, liquid, lotion and swabs. The American Academy of Dermatology indicates that clindamycin may also be combined with benzoyl peroxide (in one medication) to decrease risk that patients will develop bacterial resistance to this antibiotic. The AAD notes that when used topically, clindamycin, which has a longstanding history of use in acne treatment, is safe and tolerated well.
Proper Use
Depending on the preparation and brand, topical clindamycin may be applied either once or twice daily. Use topical clindamycin as directed by your doctor, applying no more or less of the medication than specified and no more frequently than directed. Dry, scaly, flaking skin are the most common side effects associated with topical clindamycin, the Mayo Clinic says. Contact your doctor if side effects are severe, or if you notice others such as rash, itching, diarrhea, stomach pain, nausea/vomiting, fever or excessive thirst. Skin irritation can be reduced by washing with a mild cleanser, the Mayo Clinic says, as well by as waiting 30 minutes after shaving or washing before application. Topical clindamycin should be used for as long as your doctor recommends treatment.
Other Applications
Clindamycin may also be prescribed in cream or suppository form to treat bacterial vaginal infections. Again, the medication must be used for the recommended full course of treatment for effective resolution. Clindamycin does not treat fungal or yeast infections, the Mayo Clinic says.
