Venlafaxine (Effexor) is a prescription antidepressant in a class of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Effexor is used to treat many different mood disorders, such as depression and anxiety. Effexor works by helping to stabilize and balance the brain's use of serotonin and norepinephrine. Like many medications on the market today, very rare but serious side effects can occur with this medication.
Serotonin Syndrome
Serotonin syndrome occurs when medications you take allow the chemical serotonin to build up in the body. Too much serotonin can be lethal to your system. The Mayo Clinic reports that symptoms of serotonin syndrome usually present within hours of starting a new drug. These symptoms include agitation, confusion, rapid heart rate, dilated pupils, heavy sweating and loss of coordination. Severe serotonin syndrome is a medical emergency. Symptoms of severe serotonin syndrome are seizures, high fever, irregular heartbeat and unconsciousness.
Suicidal Thoughts or Behavior
In November of 2006, the American Journal of Psychiatry published a study conducted by Dr. Gregory E. Simon, M.D., M.P.H. that stated the only drug to show a clinically significant increase in suicidal thoughts was Effexor. SAVE.org tells us that often, in patients who are severely depressed, there is a plan to commit suicide, but the depression is so great, they lack the effort needed to carry it out. However, once a patient starts on an antidepressant, the drug sometimes allows just enough energy to carry out the previous plan. This usually starts about two weeks into treatment when the drug is beginning to build up in a patient's system. No one can say with certainty why antidepressants can cause suicidal behavior in adults and children, but if you suddenly begin having thoughts or feelings about ending your life, call your doctor immediately.
Severe Allergic Reaction
As with any drug, there is a slight chance of a severe allergic reaction. Symptoms of an allergic reaction to Effexor include rash, itching, swelling, dizziness and trouble breathing. If you experience any of these symptoms, seek out medical attention immediately as some reactions can lead to anaphylactic shock and death.
Drug Interactions
Effexor should be avoided if you are taking MAO inhibitors. Notify your doctor before you start taking any new medication, including over-the-counter medicines and herbal supplements. Many over-the-counter cold medicines have a seritonergic effect, which can increase the potential of serotonin syndrome.
Member Comments