A number of prescription weight-loss medications have become available to consumers. They provide an option for people who aren't able to lose weight through conventional methods alone and for people with certain medical conditions. According to the Weight-control Information Network (WIN), weight-loss medications should only be used by people at high risk for weight-related medical conditions or whose body mass index (BMI) exceeds 29. For best results, seek guidance from your doctor.
Sibutramine (Meridia)
Sibutramine (Meridia) is a prescription weight-loss medication that works by altering a person's brain chemistry to increase satiation and suppress hunger. According to the Mayo Clinic, people who take sibutramine lose an average of 5 to 10 percent of their initial body weight after one year of taking it. Sibutramine is approved by the Food and Drug Administration (FDA) for long-term use, or up to one year. Potential side effects of sibutramine include increased blood pressure, rapid heartbeat, headache, dry mouth, constipation and difficulty sleeping.
Orlistat (Xenical)
Orlistat (Xenical) is approved by the FDA for weight loss among adults, children and adolescents. As a lipase inhibitor, orlistat works by blocking fat absorption and digestion in the stomach and intestines. Unabsorbed fat is eliminated from the body through stool. According to the Mayo Clinic, average weight loss produced by orlistat is roughly 5 to 10 percent of a person's starting body weight after one year of taking it. Since orlistat also blocks the absorption of some nutrients, a multi-vitamin is often encouraged while taking the medication to prevent nutrient deficiency. A nutrient-rich diet, based on fruits and vegetables, can also help. Orlistat may cause gastrointestinal side effects, such as abdominal cramping, diarrhea, oily and frequent bowel movements, urgency to have bowel movement and flatulence with discharge (anal leakage). Adhering to a low-fat diet may reduce these side effects. Doctors may prescribe orlistat for people with high blood pressure or heart conditions, since other weight-loss medications can exacerbate these conditions.
Diethylpropion
Diethylpropion is a prescription weight-loss medication that works by reducing a person's appetite. It is intended for short-term use, or for a maximum of 12 weeks. Diethylpropion comes in regular and extended-release (long-acting) tablets, which are taken three times daily, an hour before meals. Since diethylpropion is recommended for short-term use, doctors may prescribe it for people seeking a "jump start" to their weight-loss program. While taking it, a reduced calorie diet and regular physical activity are recommended for best results. Possible side effects of diethylpropion include dizziness, headache, sleeplessness, anxiety and nervousness.
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