Augmentin 875 mg is a combination antibiotic containing amoxicillin and clavulanic acid. It is commonly used to treat a wide variety of bacterial infections. Like most medications, Augmentin may cause a number of side effects, some of which may be serious and warrant additional treatment.
Diarrhea
Diarrhea is the most commonly reported side effect of many antibiotics, including Augmentin. In most cases, diarrhea or loose stool will subside after the medication regimen is completed. In some cases, the development of severe diarrhea may indicate the occurrence of a more severe condition involving the secondary infection of the intestines with the Clostridium difficile bacteria. Clostridium difficile associated diarrhea (CDAD) may lead to dehydration, inflammation of the colon and in rare cases, death if left untreated. In some cases, CDAD may not develop until after the medication is discontinued. While most cases of Augmentin-related diarrhea may be treated with additional fluid intake, watery or bloody diarrhea should be reported to a physician immediately.
Nausea
Nausea and vomiting are also common side effects of many medications, including Augmentin. Some patients may also experience generalized abdominal pain or cramping while taking Augmentin. In many cases, these side effects may be minimized by taking the medication with food. If vomiting becomes severe, medical attention may be needed to minimize fluid loss.
Allergic Reactions
Rash or other symptoms of allergy may occur when taking penicillin-type antibiotics. Patients who are allergic to any type of penicillin should not take Augmentin. Common symptoms of allergy may include rash and itching, while more severe symptoms may include swelling of the lips or tongue along with difficulty breathing. Allergic symptoms affecting breathing will require immediate medical attention, as anaphylactic reaction may occasionally lead to death. In addition, antibiotics such as Augmentin may rarely lead to the development of Stevens Johnson syndrome (SJS) which includes the development of a bullseye-type rash and may lead to the development of a rare, but sometimes fatal adverse reaction known as toxic epidermis necrolitis syndrome (TENS). Any symptoms of allergic reaction should be reported to a physician immediately.
Vaginitis
Many antibiotics, including Augmentin may suppress natural, healthy bacteria that exist on the skin, particularly in the groin area. Killing these natural bacteria may lead to an overgrowth of yeast, known as Candida albicans, resulting in a yeast infection of the vaginal or groin area. Though the condition is most common in women, it may affect men as well. Yeast infection may result in rash, irritation, itching and discharge. In many cases, symptoms will subside once the medication is discontinued. If bothersome, most cases may be treated with over-the-counter antifungal medications, but if symptoms are severe or persistent, medical attention may be warranted.



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