Coenzyme A is not truly an enzyme, notes Dietary Fiber, an online compendium of nutritional information. In fact, it’s an enzyme helper, and a variety of metabolic enzymes responsible for processing nutrients into energy depend upon coenzyme A in order to function. Deficiencies in this essential biomolecule, while rare, are suspected by some to lead to fatigue, muscle soreness, and metabolic disorders. Coenzyme A supplements may be beneficial in preventing symptoms of deficiency.
According to The Healthier Life, coenzyme A is vital for the production of the hydrocortisone, the anti-stress hormone. Stress can manifest itself in many unpleasant ways, and some of the symptoms of coenzyme A deficiency include depression, anxiety, an impaired sense of balance, irritability, fatigue, an abnormal need for sleep and a deterioration of the immune system. The Healthier Life website suggests coenzyme A supplementation to prevent and reduce the severity of stress symptoms.
Electronic Healing, a website that provides information on vitamins and supplements, states that coenzyme A is required to metabolize fat, carbohydrates and protein, converting them into energy at the cellular level. Electronic Healing notes that the Krebs cycle, responsible for the majority of cellular energy production, is initiated by coenzyme A. Further, a deficiency of the coenzyme can block the energy cycle and lead to a variety of metabolic disorders.
Coenzyme A is necessary to the function of other important enzyme and coenzymes, Electronic Healing notes. Coenzyme A is the vital catalyst needed to utilize Coenzyme Q10 and other energy-producing metabolic enzymes. Without coenzyme A, Co-Q10 can’t function, which is significant given the connection between Co-Q10 and heart conditions, muscular dystrophies, Parkinson's disease, cancer, diabetes and HIV.