Nausea is a common complaint during pregnancy. It is often referred to as morning sickness, but it can occur at any time of the day or night, and sometimes lasts the entire day. There are a number of natural cures thought to help nausea, like ginger and sour hard candies. Sadly, when these remedies do not work, a woman may have to resort to medications, especially if she is suffering from such severe morning sickness that she loses weight or her doctor fears for the safety of the unborn baby. Nausea medications should only be taken during pregnancy under the strict advice of a doctor.
Pyridoxine and Doxylamine
Pyridoxine (vitamin B6) alone or used in conjunction with doxylamine (a sleep aid) has been shown to effectively reduce vomiting, as indicated by Up to Date, a peer-reviewed, evidence-based health information service. The medication specifically formulated with these two drugs combined is no longer available in the United States. This combination of medicines should only be used when directed by a medical care provider. The Food and Drug Administration has determined that this combination of over-the-counter medications is safe for treating pregnancy-related nausea.
Antiemetics
Antiemetics such as prochlorperazine and chlorpromazine have been shown to be effective in relieving nausea and vomiting in pregnancy, according to American Family Physician. These medications can be given orally, rectally and via injection. Different types of antiemetics, such as droperidol and diphenhydramine, are more effective in curing severe nausea and vomiting in pregnancy, reports American Family Physician.
Antihistamines and Anticholinergics
Antihistamines are typically used to treat allergies or allergic reactions to certain agents. They have been found to be more effective than a placebo for controlling nausea and vomiting in pregnancy, per American Family Physician. Anticholinergics were once thought to be linked to cleft lip and palate in babies, but American Family Physician states a follow-up study did not find supporting evidence.
Metoclopramide
Metoclopramide is a medication that suppresses nausea by increasing the pressure against the lower esophageal spinchter and speeding the passage of food through the stomach. The lower esophageal sphincter is the flap that is found at the base of the esophagus where it meets the stomach. The flap is responsible for keeping food and stomach contents in the stomach instead of allowing them to return up the esophagus and into the mouth.


