Typically used as an alternative medicine herbal supplement for the treatment of minor fevers and infections, Andrographis paniculata can be administered to patients in the form of a pill, powder or liquid extract, according to the University of Maryland Medical Center (UMMC). However, supplement users looking to include this herb in their regimen should be aware of possible side effects.
Digestive Irritation
One major side effect experienced by users of Andrographis paniculata as an herbal remedy for minor disorders includes stomach irritation. According to the University of Michigan Health System (UMHS), some people tend to develop intestinal upset or indigestion shortly following initial consumption of the herb. Other side effects associated with the digestive system include bloating, nausea, vomiting and diarrhea. In order to limit the onset of these digestive adverse effects, patients starting treatment with Andrographis paniculata are encouraged to take the herb along with meals or on a full stomach.
Liver Side Effects
Another less-common side effect seen in supplement users taking Andrographis paniculata is irritation of the liver. According to UMHS, a trial conducted with the herb on patients diagnosed as HIV-positive reported numerous side effects, including headaches, a metallic taste in the mouth and elevated liver enzymes. These elevated enzymes can be dangerous to patients suffering from an autoimmune disease or who have a history of alcohol abuse, due to a higher risk of liver disease. In order to prevent the onset of liver symptoms, UMHS recommends a dosage of 11.2 mg per day of Andrographis paniculata.
Additional Side Effects
According to the Memorial Sloan-Kettering Cancer Center, Andrographis paniculata may also cause numerous minor adverse reactions in users of the supplement. The more common side effects include headache, fatigue, minor allergic irritation of the skin or throat, pain in the lymph nodes (especially around the jaw) and altered taste or loss of taste. Allergic reactions can occur, and in very rare instances there is the possibility of anaphylactic shock. As with any new medication, patients are encouraged to discuss any adverse effects with a medical professional.
