Ensam Side Effects

Ensam Side Effects
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Emsam (selegiline) is a transdermal antidepressant medication indicated to alleviate symptoms associated with a mental disorder called depression in adult patients. This medication is part of a class of drugs called monoamine oxidase inhibitors (MAOIs) and works by regulating the levels of certain mood-balancing chemicals--called norepinephrine, serotonin and dopamine--within the brain. Talk with a doctor or pharmacist about Emsam side effects before beginning treatment.

Application Site Reaction

Ensam is a type of transdermal medication that is applied directly to the skin once each day. Three different doses of this medication are available: 6 mg, 9 mg or 12 mg. While using this medication, certain patients develop skin reactions at the site of application. The skin can appear unusually red or irritated following treatment, explains Drugs.com, a peer-reviewed drug information website for consumers. The affected skin region can appear inflamed and may begin to itch. Contact a doctor if these application site skin reactions persist or worsen with continued use of the Emsam patch.

Mood or Behavioral Changes

During treatment with Emsam, patients can develop unusual side effects related to mood or behavior, explains PDR Health, a medical information website supported by the publishers of the Physicians' Desktop Reference. Patients with a history of bipolar disorder can develop erratic mood changes referred to as mania or hypomania during treatment. Use of this medication can also worsen symptoms of depression in certain patients. Speak with a doctor immediately if suicidal thoughts arise while using the Emsam patch.

Blood Pressure Alterations

A sudden increase in blood pressure--called a hypertensive crisis--can occur in certain patients taking Emsam. The symptoms of a hypertensive crisis develop suddenly and can include severe headache, profuse sweating, confusion, increased heart rate, stiff neck or nausea. These side effects can be life-threatening and require immediate emergency medical intervention.
To avoid experiencing these side effects, the U.S. Food and Drug Administration requires patients using the 9 or 12 mg daily Emsam dose to avoid foods or beverages that contain high levels of tyramine during and two weeks after treatment. Examples of tyramine-rich foods to avoid include aged cheeses, beer (tap or non-pasteurized), sauerkraut, pickled herring, sausage, salami or spoiled meats. These dietary restrictions are not required for patients using the 6 mg Emsam patch.
Alternatively, certain patients using Emsam can experience abnormally low blood pressure as a side effect of treatment. A decrease in blood pressure can cause episodes of lightheadedness or dizziness, which can occur in conjunction with headache or blurred vision. These side effects can affect a patient's ability to remain stable while walking and may increase the risk of sustaining an injury due to falling or tripping.

References

Article reviewed by RAS Last updated on: Apr 28, 2010

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