So many of today's prescription and over-the-counter medication was once an old herbal remedy favorite and through clinical trials they were proven so effective they went commercial. Clinical trials help refine thoughts on how an herb works to real laboratory testing to check for accuracy and the herb's effectiveness. Many common herbs for natural health are tested and found to be useful while many others fail.
Eyebright
Eyebright has been used medicinally since at least AD 64 when Dioscorides prescribed it for eye infections. Topically it works in Europe for eye infections and internally for sinusitis. It has not been evaluated by the U.S. Food and Drug Administration. According to Wellness.com, more studies are needed to check for effectiveness with pinkeye or as an anti-inflammatory. Side effects include itching, redness of eye, swelling of eye and changes in visions. Other effects include toothache, headache, sneezing, yawning, nausea, constipation, insomnia and confusion. It may lower blood glucose readings so diabetics and hypoglycemics should take caution when using eyebright.
Jackfruit
Jackfruit contains lectins that have shown antiviral, antifungal and antibacterial properties. Clinical studies test jackfruit for use in diabetes treatment by increasing glucose tolerance. According to Wellness.com, more studies are needed to fully test the theory of jackfruit and its use in glucose tolerance. Side effects include possible increased coagulation of blood, lack of sex drive or performance, or have immunostimulative effects.
Evening Primrose Oil
Clinical testing for evening primrose oil has been for ailments where essential fatty acids are lacking. According to Medline Plus, a service of the National Institutes of Health, it shows promise as a treatment for eczema. Other areas where more clinical research is needed for evening primrose oil include for breast cysts and cancer, bronchitis and breast pain. Side effects include seizures in those with a seizure disorder, headache, nausea, stomach pain and loose stools.
Elderberry
Elderberry is a European native which has its flowers and berries used medicinally. The National Center for Complementary and Alternative Medicine (NCCAM) states small studies show promise for flu symptom relief but more testing is needed to confirm. Side effects of elderberry include diarrhea, nausea and vomiting.



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