What Are the Side Effects of Asacol?

What Are the Side Effects of Asacol?
Photo Credit red pills image by Igors Leonovs from Fotolia.com

Asacol, brand name of mesalamine, is a prescription medication indicated for the treatment of mild to moderate ulcerative colitis. Ulcerative colitis is an inflammatory bowel disease that has no known cause. Initially, ulcerative colitis affects the rectum and progress to the colon, which is the lower part of the intestines. Some of the symptoms include fatigue, loss of appetite, weight loss, rectal bleeding, and skin lesions. The action of Asacol on the body is not fully understood, but it prevents the chemicals in the body from causing inflammation in the colon or rectum. This, in turn, prevents recurrence of the disease. Many side effects may be seen with this medication; any concerns should be discussed with a physician.

Headache

One of the most common side effects of Asacol is headache. It may occur in up to 14 percent of individuals, reports the "Drug Information Handbook." A pain reliever, such as acetaminophen or ibuprofen may help to alleviate the headache. However, before a patient takes any over-the-counter medications, he should discuss his options with a physician or pharmacist to ensure the best care. If pain relievers do not help or if the headache worsens, the individual should call his physician right away.

Abdominal Pain

Abdominal pain may occur with the use of Asacol. About 18 percent of individuals may experience abdominal pain. Taking Asacol with a meal may help alleviate this unwanted effect. The enema causes less abdominal pain, 8 percent, as opposed to the oral form; if the abdominal pain poses great discomfort, the patient should contact a physician about possibly switching dosage forms. Chewing gum or eating small frequent meals may also help with the pain. If severe abdominal pain occurs or if abdominal pain is accompanied by diarrhea, the patient should seek medical attention as soon as possible.

Belching

Belching may also occur with the administration of Asacol. According to the "Drug Information Handbook," about 16 percent of individual may develop belching. It is important to speak with a health care provider if this becomes bothersome or uncomfortable.

Pharyngitis

Pharyngitis, which is the inflammation of the throat, may be present in users of Asacol. About 11 percent of users may develop pharyngitis. Pharyngitis is characterized by sore throat and difficulty swallowing. Pharyngitis may also develop from a bacterial or viral infection; therefore, if these symptoms occur, it is important to inform a health care provider to ensure no further medical intervention is necessary.

Rash

Another side effect that may occur with the use of Asacol is a rash. About 6 percent of individuals may develop a rash when taking the oral form of the medication. If an individual taking Asacol develops a rash, redness, or itchiness, it may be a sign of an allergic reaction. If any of these symptoms are accompanied by shortness of breath or chest pain, immediate medical help should be sought as this may be a life-threatening allergic reaction.

References

  • "Drug Information Handbook 15th Edition"; Lacy, Charles F., Armstrong, Lora L., et al; 2007
  • "Pharmacotherapy: A Pathophysiologic Approach"; Dipiro, Joseph T., Talbert,Robert L., et al; 2008

Article reviewed by David Fisher Last updated on: May 6, 2010

Must see: Photo Galleries

Member Comments