The drug generically named pimozide is marketed in the United States under the trade name of Orap. This medication works by blocking the dopaminergic receptor sites within the brain. It is a medication used in the treatment of Tourette syndrome in which the patient does not respond to other standard forms of treatment. This medication helps suppress the neurological tics, uncontrolled vocalizations and body movements, associated with this disease process.
Speaking Problems
The person taking Orap to help control his Tourette syndrome dysfunctions may experience some common serious side effects of the drug. He may find it more difficult than usual to speak. While the medication helps to control unwanted vocalizations, if it causes him a problem with normal speech, it may indicate a serious problem with the drug. He, or those around him, should consult his physician as soon as possible about this side effect, the Mayo Clinic recommends.
Arrhythmia
Orap also may induce heart rhythm problems known medically as arrhythmias. This drug may cause the person's heart to beat irregularly, or it may cause her tachycardia, which is an acceleration of her heart rate beyond the norm. These, too, are classified as serious common side effects of Orap that need medical attention, the Mayo Clinic states.
Motion Difficulties
When he takes Orap, the person who suffers from Tourette syndrome may find his normal bodily motions changed. For example, he may become unable to control his balance. He may not appear to have expressions on his face. He also may walk with a shuffle and his normal movements may slow down. His legs and arms may become stiff and his hands and fingers may tremble. These symptoms can indicate serious problems, so consulting his physician right away is in his best interest, the Mayo Clinic reports.
Constipation
There also are a few common side effects of Orap that are not categorized as serious, Drugs.com reports. Among these includes constipation. It results because of the slowing down of fecal material within the intestines, usually because there is not enough liquid for smooth transport. In most cases, constipation will continue only for several days after starting treatment with Orap.
Drowsiness
Drowsiness is a common, non-serious side effect of Orap, Drugs.com reports. It occurs because of the body's adjustment to the new medication and typically lasts temporarily when beginning the drug treatment.



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