Official partner of the LIVESTRONG Foundation

Enzymes for the Treatment of Psoriasis

May 16, 2010 | By Jennifer McVey RD, LD

Jennifer McVey is a Cardiovascular-Thoracic Surgery and Oncology Registered and Licensed Dietitian at UT Southwestern Medical Center in Dallas, Texas. She earned degrees in clinical dietetics from UT Southwestern and nutritional sciences from Texas A&M University. McVey has been the guest speaker and writer for several community health fairs, events, websites and blogs. She has also been published in national newsletters and articles.

Psoriasis is a skin disorder.
Photo Credit skin image by Robert Kelly from Fotolia.com

Psoriasis is a skin disorder, generally manifested in the form of skin inflammation and pruritus. It further causes abnormal proliferation of the affected part of the skin; a scaly plaque may appear. The cause is an abnormal immune system. The main affected parts are the elbow, knee joints even scalp. The allergic manifestation is the most troublesome symptom in this case. It also causes a social embarrassment to the patient.

Possible Therapy to Treat Psoriasis

The therapy is dependent on the physical condition of the patient. Some therapies are likely to cause liver or kidney disorders, and high-risk patients should be monitored accordingly before initiating any therapy. Some enzymes are showing very positive results in treating psoriasis.

Fish Enzyme in Alleviating the Symptoms of Psoriasis

Some of the fish eggs contain a very important enzyme called zonase. This enzyme has a quality to break the fibrous tissue of the dead and affected cells of the target areas. It thereby helps to remove the dead protein and the scaling plaque type of tissue, and gradually normal skin cells start appearing. The chances of developing abnormal cells are also diminishing with the continuous use of zonase.

Main Source of Zonase

Salmon fishes are the main source of zonase. The collagen of the eggs gives rise to this enzyme. Once isolated, it needs modern technology to extract this enzyme. After further purification in a laboratory, zonase is made available commercially.

The Presentation of Zonase

Zonase is mainly used as topical preparation. The medium is generally gelatin. Any enzyme needs some watery substances on the area of action. Without the friendly environment, the medicine can't act properly. However, the gelatinous substance helps keep the skin moist for some time, and the enzyme can exert its effect in more predictable ways.

Mode of Application of Zonase

The patient should use this preparation two to three times daily on the affected parts. The applying process should be gentle, lest there be some chance of tearing of the dead tissue and oozing of blood.

The Limitation of Zonase

Sometimes, in topical form, the gelatin base is not found to be adequate to moisten the area adequately. This may partially result in drug failure. The preparation is for long-term use, which may sometimes reduce the patient's compliance and consequently bring inadequate relief.

References

Article reviewed by Anton Alden Last updated on: May 16, 2010

Must see: Slideshow & Video