Remicade, the brand name of the generic infliximab, is a monoclonal antibody medication. Monoclonal antibodies are scientifically engineered antibodies developed in laboratories that mimic natural antibodies produced by the body. Before Remicade is prescribed, a physician must determine that the patient has no infections or immune disorders. Remicade/infliximab is given intravenously and can only be obtained with a prescription.
Function
Remicade reduces inflammation in the body. It is used to treat diseases such as ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis and Crohn's disease. It is helpful in diseases where the body's own antibodies attack healthy tissues. Monoclonal antibodies can attach themselves to certain cells to block or disrupt growth, make target cells more visible or deliver strong medications directly into the cells.
Effects on the Immune System
Remicade may also reduce the number of blood cells that fight infection. Because of this, a person's resistance to certain infectious diseases may be drastically inhibited due to Remicade. The medication can also increase the chance of bleeding when an injury occurs. Some vaccines have "live" cultures and should not be used if Remicade is being prescribed for other severe illnesses.
Side Effects
Shortness of breath, flu symptoms, ongoing coughs and a sore throat should be reported to a physician immediately. Because Remicade reduces the body's ability to fight off infection, exposure to viruses may cause a severe reaction. Hives, difficulty breathing, swelling of the face, tongue and throat are all considered to be dangerous allergic symptoms and should be evaluated by emergency professionals as soon as possible.
Miscellaneous Issues
Congestive heart failure, COPD, or chronic obstructive pulmonary disease, and epilepsy may call for reduced dosages or discontinuation of the medication. Recent bouts with infections or viruses may cause a physician to discontinue Remicade treatments until the illness is gone.
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