Nystatin is a prescription medication used to treat fungal infections on the skin, mouth and any moist areas such as the vagina. It works by attaching to the cell wall of the fungi and causing the contents to leak through; this will lead to death of the fungal cells. Although generally well tolerated, nystatin may produce side effects in some individuals. Any concerns should be discussed with a health care provider to ensure safety.
Nausea and Vomiting
Nausea and vomiting are common side effects that may occur with the use of nystatin. The "Drug Information Handbook" reports that up to 10 percent of patients may experience these undesired adverse effects. Large fatty meals may aggravate these side effects so it proves best to eat small, frequent meals. The patient may also try chewing gum or sucking on hard candy to alleviate nausea. If the nausea or vomiting persists or worsens, the patient should speak with a health care professional. If these side effects are accompanied by fever, the patient should seek medical care to ensure further medical intervention is not needed.
Diarrhea
Diarrhea is another side effect that nystatin can cause in users. About 5 percent of patients may experience this unwanted side effect. The patient should consume an adequate amount of fluids and avoid large meals. If the stool contains blood, the patient should receive contact his physician right away. Also, if the diarrhea persists for more than 3 days or becomes severe, the patient should seek immediate medical attention. A fever, which accompanies diarrhea may indicate a more serious infection and should receive immediate professional care, as well.
Stomach Pain
Nystatin may also produce stomach pain in about 5 percent of individuals, states the "Drug Information Handbook." If a patient experiences this side effect, he should attempt to take the medication with a meal. Food may help to alleviate or prevent the stomach pain in some cases. However, if the pain becomes persistent and bothersome, the patient should seek medical advice to ensure it is not a serious medical issue. Furthermore, the physician may switch the medication to a safer alternative.
References
- "Drug Information Handbook 15th Edition"; Lacy, Charles F., Armstrong, Lora L., et al; 2007
- "Pharmacotherapy: A Pathophysiologic Approach"; Dipiro, Joseph T., Talbert,Robert L., et al; 2008


