Alpha lipoic acid is a potent antioxidant that is produced in the body naturally. Dietary sources of alpha lipoic acid include red meat and yeast. It is also available in a supplemental capsule form. Supplemental alpha lipoic acid protects against free radicals, promotes blood glucose levels and prevents cognitive decline, all with very few side effects.
Unique Antioxidant
Alpha lipoic acid remains a relatively unknown, yet powerful antioxidant that can be more potent than other antioxidants such as vitamins C and E, according to researchers at the University of California at Berkeley. As a powerful antioxidant, alpha lipoic acid neutralizes harmful free radical compounds that are known to promote cancer and other diseases. Researchers at Berkeley report that alpha lipoic acid aids the body by preventing cell destruction and stimulating the production of the amino acid glutathione, another antioxidant. Studies from Berkeley found that alpha lipoic acid increased survival rate and improved tissue damage in sick rats. The studies found that alpha lipoic acid is unique because it is both fat- and water-soluble, meaning it can be transported to and protect all the parts of the cell.
Diabetes Treatment
Research at the Linus Pauling Institute at Oregon State University shows evidence that the antioxidant may be beneficial for individuals suffering from type 2 diabetes mellitus. Diabetes mellitus is characterized by elevated blood glucose levels. Individuals with type 2 have impaired glucose uptake, and research reports that alpha lipoic acid can improve blood sugar utilization. Individuals who were administered alpha lipoic acid orally showed an increased sensitivity to insulin and lower complications normally associated with diabates. The University of Maryland Medical Center reports that the antioxidant may reduce symptoms of pain, tingling and numbness in individuals suffering from nerve damage caused by diabetes mellitus.
Cognitive Decline Prevention
Alpha lipoic acid has been reported to improve cognitive measures, according to the Linus Pauling Institute. Cognitive decline is associated with decreased memory, motor and language skills. Individuals suffering from Alzheimer's disease reported that oral supplementation of alpha lipoic acid for one year prevented cognitive decline. Researchers from the Linus Pauling Institute note that studies show that alpha lipoic acid prevents age-related cognitive decline and cognitive impairment normally associated with dementia and other cognitive disorders.
Side Effects and Interactions
The Linus Pauling Institute reports that there are few serious side effects with alpha lipoic supplementation. Intravenous administration at 600 mg per day and orally at 1,800 mg per day did not result in adverse side effects. Oral alpha lipoic acid has been reported to cause some allergic reactions that affect the skin, such as hives and rashes. Other side effects include gastrointestinal complications such as abdominal pain, nausea and diarrhea. Individuals diagnosed with diabetes who take medication should consult a physician first before taking alpha lipoic acid.
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