AML, or acute myelogenous leukemia, is a type of cancer that develops acutely and affects the blood and bone marrow. AML grows quickly, causing the bone marrow to make abnormal white and red blood cells and platelets that interfere with the body's ability to fight infection, clot blood and deliver oxygen to the body's tissues. Symptoms of AML typically include frequent infection, bleeding and joint and bone pain.
Frequent Illness
According to the National Marrow Donor Program, people with acute myelogenous leukemia may have an abnormally low number of white blood cells, making it more difficult to fight off infection. As a result, frequent, severe or recurrent infections can occur. These infections are often accompanied by a fever.
Low red blood cell count is also common among those with AML, leading to anemia--a condition in which insufficient blood and oxygen circulate to the body's tissues. Because the body does not have the energy it needs, patients may develop symptoms such as pale skin, shortness of breath during physical activity, a rapid heart rate, extreme fatigue and muscle weakness. According to the Mayo Clinic, chronic malaise and illness can also lead to weight loss.
Bleeding and Bruising
According to The Leukemia & Lymphoma Society, people with AML may suddenly find that they bleed and bruise very easily. They may notice black-and-blue bruises on the body in the absence of any clear trauma or injury. Cuts may be slow to heal or may bleed excessively and fail to clot within a usual period of time. Some people also develop petechiae--small red dots on the skin that are signs of bleeding just under the skin's surface. The Mayo Clinic advises that frequent, unexplainable nosebleeds or bleeding from the gums may also be symptoms of AML leukemia.
Pain
Acute myelogenous leukemia can cause pain in various locations throughout the body. According to KidsHealth.org, some people may develop abdominal pain caused by an abnormal buildup of blood cells in organs in the abdominal region, including the spleen, liver and kidneys. AML leukemia can also causes aches and pains in the joints or bones in the legs, knees, arms and shoulders.
Chloromas
According to KidsHealth.org, some children with acute myelogenous leukemia may develop chloromas--lumps of leukemia cells that form anywhere in the body and can be felt beneath the skin. Usually painless, they commonly occur in the underarm or groin area and neck.
