1. Determine the Cause
Anisocoria can be caused by a wide array of conditions ranging from Horner's Syndrome, which can be deadly, to oculomotor nerve palsy to benign mechanical problems. Unless and until you can isolate the root cause of the problem, your therapies and management techniques may be off the mark and may do more harm than good. In fact, by treating the wrong cause, you may delay treatment of the root problem.
2. Management of Anisocoria Caused by Horner's Syndrome
First off, you need to determine whether or not you have Horner's Syndrome. Ophthalmologists use a solution of 10 percent cocaine to search for the disorder. If your doctor detects Horner's Syndrome, many treatment pathways may be suggested. If a recent stroke led to the syndrome, you may need to treat the cause of the stroke and repair/prevent further neurological damage. If there is some kind of tumor at work, either in the lung or along the cervical spine, you will need to treat the problem with an oncological specialist. If you have what is known as a "cavernous sinus disorder," you may need to treat that in order to relieve your Horner's Syndrome and thus cure the anisocoria.
3. Treat Your Oculomotor Nerve Palsy
The so-called third nerve palsy is different from other types of nerve palsies which typically afflict diabetics. Talk to your physician about devising and executing a plan of therapy.
4. Stop Taking Certain Pharmacological Medications
Anisocoria can be brought on by certain pharmacological medications, such as eyedrops or even inhalers used to treat asthma. By getting off these medications, you may be able to resolve the condition.
5. Diagnose and Possibly Repair Mechanical Iris Damage
If the iris gets inflamed, torn during surgery or otherwise traumatized, anisocoria can result. If your condition is caused by some mechanical issue, you may be able to take medication to relieve inflammation, or you may be instructed to wait it out and allow time to heal the traumatic damage.


