Remicade, or infliximab, is a medication used to treat inflammation in the body. It is often a second-line treatment; that is, doctors often prescribe it after other treatments have failed. According to Drugs.com, Remicade is used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, Crohn's disease, ankylosing spondylitis, and severe psoriasis.
Headache and Nasal Congestion
According to Drugs.com, patients taking Remicade may experience a headache, nasal congestion, and sinus pressure and pain. These side effects may subside after the body has time to adjust to treatment with Remicade. Users should consult their physician to determine if they may use an over-the-counter pain reliever such as acetaminophen or ibuprofen. Using a saline nasal wash or spray or taking a steamy shower may help to relieve sinus discomfort. If sinus pain and pressure is accompanied by fever or yellow or green nasal secretions, it can be a sign of a sinus infection, which may require treatment with an antibiotic.
Skin Rash
Remicade may cause the development of a mild skin rash or psoriasis. According to the manufacturer, psoriasis appears as red scaly patches or raised bumps on the skin that are filled with pus. In severe cases, a red, purple, or scaly skin rash can occur. If a skin rash or hives appears along with difficulty breathing or swelling of the tongue or throat, it may be the sign of an allergic reaction to Remicade. These side effects should be reported to a health-care provider immediately.
Increased Risk of Infection
Remicade may decrease the body's immune reaction against certain illnesses, making patients more prone to developing an infection, such as tuberculosis or pneumonia. According to Remicade, symptoms of an infection can include fever; tiredness; cough; warm, red or painful skin; or any open sores. Patients taking Remicade should be instructed to avoid contact with sick persons while taking this medication.



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