1. Start With the Least Invasive Options
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed medicines to treat reactive arthritis. In most cases, patients seem to react well to these, which is why doctors are usually weary of moving on to more invasive drugs. Most of these medications are available over-the-counter, such as the case of aspirin or piroxicam (Feldene).
For people suffering flare-ups or experiencing intense pain, doctors may prescribe a short treatment of corticosteroids, which often has a rapid effect on inflammation but come with some serious side effects including increases in blood sugar, cataracts and brittle bones, especially if used repeatedly or for long periods of time. For people who are especially sensitive, a shot of corticosteroid given directly on the inflamed area may be a better option than taking the drug orally.
2. Treat the Joints
While non-steroidal anti-inflammatory drugs can help alleviate symptoms in any part of the body, certain medications will directly reduce the swelling and inflammation because they treat the overall symptoms, rather than the disease itself. A clear example is the group of drugs known as sulfasalazine or anti-rheumatic drugs. These are made to be used over long periods of time and will help manage rather than control the symptoms. They are usually not strong enough to control flare-ups or intense pain or swelling.
3. Be Aware of Interactions
Because reactive arthritis often shows up after you start recovering from a serious infection or the diagnosis of an immune disease such as HIV, it's important that you are properly instructed on what drugs you can and cannot take. For example, the drug methotrexate (Rheumatrex) is often prescribed to patients who suffer intensive pain as a result of reactive arthritis. However, since the drug suppresses the immune system, it should not be taken by people who have HIV or AIDS.
