Propofol is also known as Diprivan and belongs to a class of drugs known as general anesthetics. The National Institutes of Health states that propofol induces and maintains anesthesia in patients undergoing surgery or painful procedures. Propofol is also used to sedate intensive care unit patients on mechanical ventilators. According to Lifeline to Modern Medicine, a website sponsored by the American Society of Anesthesiologists, propofol is a powerful drug that requires monitoring due to life threatening side effects.
Nervous System Effects
The American College of Gastroenterology, says that sedation with propofol affects reaction time and the ability to make decisions that may last for hours after a procedure. Doctors advice patients to avoid driving cars or engaging in activities that require concentration until after the day of the procedure
Respiratory Effects
According to the NIH, propofol causes slowed breathing, which leads to low oxygen levels in the blood. propofol also causes airway obstruction. ACG states that, propofol should be administered in health settings where anesthesiologists can administer oxygen check levels of oxygen frequently.
Cardiac Effects
Propofol depresses cardiac function which leads to slowed heart rate and lowered blood pressure, says the NIH. ACG states that anesthesiologists are required to monitor heart rate and blood pressure while patients are sedated with propofol.
Hypersensitivity
Patients allergic to eggs and soybean products should avoid propofol, says the NIH. Patients should seek immediate medical help if they experience allergic responses such as difficulty breathing, rash, hives, tightness in the chest, itching and swelling of the face, lips and tongue.
Propofol Infusion Syndrome
The NIH states that the use of propofol for sedation has been associated with a fatal condition known as propofol infusion syndrome. This condition can cause an enlarged liver, metabolic acidosis, hyperkalemia, cardiac failure, renal failure and rhabdomylolysis.
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