Contraindications For Kava

We use kava primarily for its rumored relaxation properties. Scientists know kava has some effect on dopamine, a vital neurotransmitter in our brain responsible for a long list of necessary daily functions--from voluntary movement to sleep to mood. Kava holds steady as one of the safer supplements in clinical testing, although as with any vitamin or supplement, contraindications exist.

Alcohol/CNS Depressants

Only a few studies exist that look at alcohol in combination with kava. One 1997 study, published in the "Drug and Alcohol Review," showed that when taken with alcohol, kava increased the effects of alcohol--probably due to its action on dopamine receptors in the brain. Because kava affects dopamine, scientists theorize that kava may strengthen the effect of other drugs that depress the central nervous system by way of dopamine, such as certain sedatives and anti-anxiety agents. Physicians warn that you should avoid kava when drinking alcohol or taking sedative-type drugs.

Antiepileptic Medication

Scientists theorize that kava also possesses an anti-seizure component. An article in "Epilepsy & Behavior" cautions against taking kava either in place of or with an antiepileptic medication. Administration of kava alone may not prevent seizures, and the combination of kava with an antiepileptic medication may cause an increase in lethargy and mental impairment.

Parkinson's Disease

People with Parkinson's disease take specific drugs to stimulate dopamine and help regulate movement. One study, published in the Journal of Neurology, Neurosurgery & Psychiatry, looked at four different patients with movement disorders and the effect of kava. Each patient showed a worsening of symptoms when taking kava, which led physicians to contraindicate kava for people with Parkinson's disease. A published report from 2002 relates the study of a woman with a genetic tremor who developed severe parkinsonism after a 10-day course of kava for anxiety.

Liver Problems

On March 25, 2002, the Food and Drug Administration issued a Consumer Advisory regarding dietary supplements that contained kava. In it, the advisory stated, "Kava-containing products have been associated with liver-related injuries--including hepatitis, cirrhosis, and liver failure--in over 25 reports of adverse events in other countries...Given these reports, persons who have liver disease or liver problems, or persons who are taking drug products that can affect the liver, should consult a physician before using kava-containing supplements."