Accutane, generically known as isotretinoin, is a prescription drug used to treat severe, cystic acne that does not respond to other acne treatments such as antibiotics. Accutane works by shrinking the pores in the skin to prevent bacterial growth and acne breakouts. While Accutane is highly effective at preventing acne, it does have a number of potential side effects, some of which may be severe. A physician should explain these side effects before the start of Accutane use.
Birth Defects
The most serious side effect of Accutane use is the risk of serious birth defects when taken by pregnant women. The American Osteopathic College of Dermatology explains that it is absolutely critical that pregnant women do not use Accutane while pregnant or while trying to become pregnant. Healthsquare.com details the potential birth defects caused by Accutane, including mental retardation and malformations of the head, mouth and skull. Most women taking Accutane will need to sign a consent form that they understand these risks before a prescription for Accutane can be filled. The birth defects caused by Accutane are so serious that physicians recommend that sexually active women using Accutane also take birth control pills to prevent pregnancy. Since birth control pills are not always 100 percent effective, it is recommended that an additional method of birth control such as a condom or diaphragm be used simultaneously with birth control pills.
Dryness of the Lips, Mouth and Nose
The most commonly reported side effect of Accutane is chapped lips. According to the American Osteopathic College of Dermatology, up to 90 percent of Accutane users will experience dry lips as a result of Accutane use. Dry lips can be treated with a lip moisturizer balm. Drugs.com lists dry mouth as another common side effect of Accutane. About 80 percent of people taking Accutane will have nosebleeds as a result of an overly dry nose or nasal cavity.
Dry Eyes
Accutane use can dry out the eyes and cause a number of eye-related side effects. MayoClinic.com explains that Accutane can cause burning, itching, redness and general inflammation of the eyes. Accutane users that wear contact lenses are particularly susceptible to eye dryness complications.
Headaches and Dizziness
Mild to severe headaches and dizziness are a common side effect of Accutane use. These headaches are typically responsive to over the counter pain relievers. MayoClinic.com recommends that patients experiencing persistent headaches from Accutane discontinue use and consult a physician. Dizziness and hearing loss are also commonly experienced by people taking Accutane.
Depression
Depression is a commonly discussed side effect of Accutane use. The incidence of depression and other mood-related side effects from Accutane is relatively rare, however, affecting about 1 percent of Accutane users, according to Drugs.com. Individuals with a history of psychological or mood disorders should discuss these issues with a physician before beginning Accutane treatment.



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