Lupus is a chronic disease in which the immune system attacks various parts of the body, including the joints. During a lupus flare, patients may feel varying degrees of joint pain, which can last from a few days to a few months. Chronic joint pain can interfere with daily activities and lower quality of life. Though there is no cure for lupus, various combinations of medicine are used to treat the symptoms of the disease.
Over-the-Counter Medications
As a first course of treatment, the Lupus Foundation of America recommends using over-the-counter anti-inflammatory drugs and pain medicines. Reducing inflammation can help to lessen lupus related pain. Medicines like aspirin, acetaminophen, and nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen may be the only medications needed, depending on the severity of joint pain. Patients may need to try different products to determine which medicine brings them the most relief. Nonsteroidal anti-inflammatory drugs, including aspirin, may cause stomach upset or irritation.
Prescription Medications
Corticosteroids, a synthetic version of a hormone produced by the adrenal glands, is prescribed to reduce swelling, tenderness and joint pain. Steroids work quickly, but can have many possible side effects with prolonged use, MayoClinic.com notes. Some side effects of corticosteroids include weight gain, fluid retention, changes in appearance, thinning of the bones and high blood pressure. Antimalarial drugs are used to reduce inflammation, joint pain, and to control flares, though there is no known correlation between lupus and malaria. This medicine takes time to build up in the body. It can take a prolonged period of time to feel the full effects of this medication. Antimalarials may cause upset stomach, muscle weakness or changes in skin and hair color. Long-term use at high doses may damage the retina of the eye. Nonsteroidal anti-inflammatory drugs come in prescription strength, and are an option if over-the-counter strength is not sufficient.
Alternative Medicine
Alternative medicine can be used in conjunction with traditional medicine to minimize lupus joint pain. In a study conducted by The Center for Genetics, Nutrition and Health in Washington, omega-3 polyunsaturated fatty acids found in fish oil and flax seeds were found to have anti-inflammatory properties. The research, published in 2002, showed that the use of omega-3 fatty acids reduces the symptoms of lupus and lowers the amount of additional anti-inflammatory medications needed. Yucca, a medicinal herb found to be beneficial in treating of arthritis symptoms, may help to reduce lupus related joint discomfort. Yucca is a rich source of steroidal saponins and polyphenolics, which can help reduce inflammation and pain. Before starting any herbal regimen, consult with a doctor or trained professional.


