Azadirachta indica, commonly known as neem, is an evergreen tree native to India and southeast Asia that has since spread to tropical and subtropical regions throughout the world. Ayurveda, a traditional medicinal practice from India, recommends neem for several health benefits, as noted by the University of Michigan Health System. Although neem seed oil is possibly the best-known substance from this plant, neem leaves also have uses in herbal remedies.
Infections and Digestive Problems
Both ancient medical texts and modern herbalists recommend neem leaf extract for treating upset stomach and diarrhea, according to the UMHS. The University of Pittsburgh Medical Center notes that traditional uses for neem leaf include treating intestinal parasites and viral infections.
Skin Disorders
Neem leaves have antifungal, antiseptic and anti-inflammatory properties, making this herb useful for treating skin problems, as explained by Maharishi Ayurveda. Traditional Ayurvedic remedies involve crushing the leaves into a paste and applying this preparation to wounds, sores, eczema, ringworm infections and acne. Neem leaf preparations have also been used to treat leprosy, according to Drugs.com. The UMHS notes that neem leaf extract is effective against scabies, a skin infection caused by mites.
Dental Uses
A study published in the January 2004 issue of the "Journal of Ethnopharmacology" found that neem leaf extract applied as a dental gel was significantly effective against plaque and bacteria over six weeks in men aged 20 to 30. Neem extract gel achieved better results than a commercial mouthwash containing 2-percent strength chlorhexidine gluconate. Additionally, a study published in the Winter 2008 issue of the "Journal of Clinical Pediatric Dentistry" found that patients with chronic gum inflammation, or gingivitis, experienced a decrease in plaque and gingivitis after using a neem extract mouthwash for two weeks. However, the results were not statistically significant. The UMHS and UPMC theorize that neem leaf gel, mouthwash or chewing gum might be beneficial for treating periodontal disease or preventing cavities, due to its effects on plaque and bacteria.
Potential Anti-Cancer Use
Neem leaf preparations have anti-cancer properties, according to a study published in the January 2009 issue of the "Journal of Immunotherapy." Neem leaf glycoprotein was found to induce T lymphocytes, a type of white blood cell, to kill oral cancer cells. The authors explain that their results indicate neem leaf glycoprotein might be able to recover white cell function in patients with head and neck squamous cell carcinoma who have suppressed immunity.
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