Renagel is a phosphate binder prescribed for the treatment of elevated levels serum phosphorus in patients with chronic kidney disease. Patients with chronic kidney disease retain excess amounts of phosphate, a condition known as hyperphosphatemia. Elevated levels of serum phosphorus can precipitate serum calcium leading to brittle bone disease and calcification of the circulatory system. Treatment for hyperphosphatemia includes a reduction in the dietary intake of phosphate, dialysis to remove phosphate from the blood and phosphate binders such as Renegal to inhibit intestinal absorption of phosphate.
Calcium Acetate
Calcium acetate is an alternative drug to Renagel in the treatment of hyperphosphatemia in patients with chronic kidney disease. According to Rxlist.com, calcium acetate is a phosphate binder, forming insoluble complexes with phosphate ions in the gastro intestinal tract, effectively inhibiting their absorption into the blood stream.
Fosrenol
Fosrenol is a phosphate binder prescribed for the reduction of elevated levels of serum phosphorus in patients with end stage kidney disease. Similar to Renagel, Fosrenol binds to phosphate ions in the stomach and intestinal tracts forming highly insoluble complexes, effectively preventing its absorption into the blood. According to Drugs.com, in vitro studies have shown that Fosrenol binds approximately 97 percent of gastorial phosphate levels if administered with or immediately after a meal.
Calcium Carbonate
Calcium carbonate is a phosphate binder prescribed for controlling serum phosphorus levels in patients with chronic kidney disease, says Drugs.com. Calcium carbonate binds to phosphate ions in the gastro-intestinal tracks, forming insoluble complexes that cannot be absorbed in the blood and cause hyperphosphatemia.
