The history of using goldenseal root, or Hydrastis canadensis, for medicinal reasons stretches back hundreds of years. Native Americans used the plant before settlers arrived on the shores of the Americas. While the herb remains a popular supplement in modern times, scientific evidence supporting its use is scarce. Before taking goldenseal, consult a qualified practitioner for advice.
Basics
The goldenseal plant is native to North America, particularly the Pacific Northwest. The beneficial parts of the plant are the root and the rhizome, according to the University of Michigan Health System website. Drinking goldenseal teas or tonics tends to leave a bitter taste behind. The goldenseal plant has grown increasingly rare due to over-harvesting.
Uses
Herbalists recommend goldenseal for a variety of ailments. While scientific studies have yet to confirm goldenseal's efficacy in these areas, traditional uses for the herb include disinfecting minor wounds, treating allergies, easing cold and flu symptoms, aiding digestion and clearing up inflammatory infections of the eyes, skin and mucous membranes. "Nature's Medicines" claims that the antibacterial and antiseptic aspects of the plant help it fight a wide range of infections. It may also be used for vaginitis, cold sores and canker sores.
Function
The two main active constituents in goldenseal, berberine and hydrastine, give the herb its medicinal benefits. Berberine kills bacteria, tapeworms and other parasites and may also boost the immune system by aiding white blood cells. One study in Diabetes from the Department of Biological Sciences at Seoul National University found that berberine may have antidiabetic properties because of its ability to stimulate AMPK, an important enzyme.
Usage Information
Dosage information on goldenseal is for educational purposes only. It is intended as neither recommendation nor advice and should not replace a consultation with a medical professional.
The supplement comes in capsule, tablet and liquid form. It can be taken as a rinse for oral infections, as an eyewash for eye problems or as a douche for vaginal irritation. The capsules and tablets can be taken in dosages ranging from 500 to 1000 mg. 3 mL of tincture or 30 to 120 mg of extract can be taken as often as three times per day.
Precautions
While goldenseal is a relatively safe plant, pregnant women and breastfeeding women should not take it. It may also pose a health risk for people who suffer from liver and heart problems. If you are taking a blood-thinning medication or tetracycline antibiotics, be aware that goldenseal can interfere. Common side effects include irritation and sensitivity to light.



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