There are two major forms of tuberculosis: latent, in which the infection is inactive and can't be spread to other people, and active, in which the infection is contagious. Of these, active tuberculosis is the more severe form. Patients who exhibit any of the symptoms of severe tuberculosis should seek medical care as soon as possible.
Coughing
Tuberculosis is a bacterial infection that most commonly develops in the lungs, reports KidsHealth, a children's health information website supported by the Nemours Foundation. Lung inflammation caused by the bacterium Mycobacterium tuberculosis causes coughing. Episodes of coughing can persist for longer than three weeks, according to the Centers for Disease Control and Prevention. Patients with severe tuberculosis often cough up phlegm or mucus that contains blood. These symptoms frequently cause chest pain.
Fever and Night Sweats
Patients with severe tuberculosis can develop a persistent fever accompanied by night sweats, explains AIDS.gov, an online informational resource provided by the U.S. Department of Health and Human Services. Some patients may also experience chills or headaches in conjunction with fever and night sweats. A patient's skin can appear flushed or may be warm or hot to the touch. A patient with a recurrent fever should contact his doctor, as this could also be a symptom of a different infection.
Weight Loss or Decreased Appetite
Significant, unexplained weight loss can occur as a symptom of severe tuberculosis, according to the Mayo Clinic. Patients may also have no appetite, which contributes to the weight loss.
Fatigue or Weakness
Cough, fever and weight loss can cause severe fatigue in those with severe tuberculosis, according to the Centers for Disease Control. Patients can have difficulty remaining alert and may be unable to do their jobs or go to school. Fatigue can be debilitating and may persist until patients receive long-term treatment with appropriate medication.


