Seroquel (quetiapine) is an anti-psychotic medication most commonly used to treat the symptoms of bipolar (manic-depressive) and schizophrenic disorders. At times, however, it is also prescribed in response to what are known as "off-label" conditions--those for which the drug has not yet been approved for use by the Food and Drug Administration (FDA). What exactly causes quetiapine to work toward improving psychotic conditions is unknown. Seroquel, like other anti-psychotics, blocks receptors of certain neurotransmitters in the brain, an overabundance of which is thought to be present in many psychiatric disorders.
Schizophrenia
Schizophrenia is a cognitive disorder with symptoms including delusions, disordered thinking, social withdrawal, motor impairment and hallucinations. While seroquel is not a remedy for schizophrenia, it has been shown to reduce the frequency of schizophrenic episodes.
Bipolar Disorder
Bipolar disorder (manic depression) is a serious condition marked by severe mood swings that spontaneously veer from elated highs to crippling, depressive lows. Seroquel is often used along with divalproex, or lithium, to counteract the despondent episodes of manic-depression. Seroquel blocks the brain's response to dopamine and serotonin, chemicals that are thought to exist inordinately in bipolar sufferers.
Insomnia
Seroquel is sometimes used off-label to resolve sleep disorders. It has a sedative effect that can help regulate the sleep cycles of those who are suffering from insomnia. However, seroquel typically leaves the user in a groggy state of mind upon awakening, sometimes for several hours. It is advised that you discontinue use of the drug for sleep conditions once your cycles have become regular.
Anxiety Disorders
Seroquel is also used to lower anxiety in patients with nervous disorders. The drug's drowsing effect helps calm mental disquiet and lowers negative emotions, such as fear and apprehension, that are common with issues of anxiety.
Dosages
The drug is usually taken two or three times a day, ingested orally. Small dosages are usually prescribed at first, and increased gradually as tolerance builds. Mental condition, age and medical history all play important roles in determining the appropriate medication levels. Eating grapefruit may amplify the effects of the drug, and should be avoided.
