Glimepiride is the generic name of a medication used to treat type 2 diabetes, according to MedlinePlus, a publication of the National Institutes of Health. Type 2 diabetes is a disease that typically begins in adulthood and is characterized by the body's inability to produce enough insulin or to utilize that insulin properly. Glimepiride stimulates the pancreas to make more insulin and also makes the body more sensitive to insulin. The drug comes in tablet form and is taken by mouth, usually once a day.
Hypoglycemia
The most common side effect of glimepiride is hypoglycemia, or low blood sugar. According to MedlinePlus, patients taking glimepiride should be aware of the symptoms of hypoglycemia. These symptoms include shakiness, dizziness or lightheadedness, sweating, numbness or tingling around the mouth, and pale skin. If left untreated, hypoglycemia can lead to symptoms of confusion, seizures, and loss of consciousness. Patients experiencing symptoms of hypoglycemia should seek medical attention immediately.
Dermatological Effects
Allergic skin reactions may occur while taking glimepiride, according to RXList.com. Symptoms of an allergic skin reaction include red, inflamed, and itchy skin. Hives may occur. Skin sensitivity to sunlight has also been reported. Anyone taking glimepiride who experiences symptoms of an allergic skin reaction should contact her doctor immediately for further medical advice.
Gastrointestinal Effects
RXList.com reports that glimepiride may cause some gastrointestinal side effects. These effects include nausea, vomiting, stomach pain, loss of appetite, and diarrhea. In rare cases, inflammation of the liver has occurred in patients taking glimepiride.



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