Simvastatin, or Zocor, is a medication in a class of drugs known as HMG CoA reductase inhibitors, or statins. Simvastatin works by lowering the body's bad cholesterol while raising the body's good cholesterol. This medication is also used to lower the risk of stroke, heart attack, other heart complications in people with diabetes, and coronary heart disease, reports Drugs.com. Patients should be aware of some side effects associated with simvastatin prior to starting therapy.
Muscle Pain
Patients taking simvastatin may experience muscle pain and weakness. For some, this pain may be mild and tolerable, while others may have difficulty completing everyday tasks. In rare cases, this medication can cause life-threatening muscle damage called rhabdomyolysis, according to the MayoClinic.com. Additional symptoms of rhabdomyolosis include fatigue, severe muscle tenderness, and dark cola-colored urine. If not properly recognized and treated, rhabdomyolosis can lead to liver damage, kidney failure, and death. Patients taking simvastatin should report any muscle pain or weakness to their physician immediately.
Headache
Simvastatin may cause headaches. This side effect may be temporary and diminish over time as the body adjusts to this medication. Patients can consult their physician regarding the use of an over-the-counter medication such as acetaminophen for occasional use to relieve headache pain and discomfort. If headaches become severe and are accompanied by changes in vision, difficulty speaking, or weakness one one side of the body a physician should be notified.
Gastrointestinal Discomfort
Simvastatin may cause gastrointestinal discomfort. These symptoms may lessen over time as the body adjusts to simvastatin. Symptoms can include indigestion, nausea, diarrhea, and constipation. Patients who have experienced prior digestive issues may be more likely to experience these effects. Taking a statin medication in the evening with a meal can reduce digestive side effects, says MayoClinic.com. Small dietary changes such as avoiding spicy or fatty foods and eating smaller meals more frequently can help alleviate gastrointestinal discomfort.
Skin Rash or Flushing
Patients taking simvastatin may experience a skin rash or flushing. This rash may or may not itch. According to MayoClinic.com, those who take a statin drug plus niacin are more likely to have this side effect. Patients who develop a rash while taking this medication should consult their physician for further instruction.
