Amoxicillin & Clavulanate Potassium

Amoxicillin is an antibiotic in the penicillin family. Clavulanate potassium is an ingredient that helps to overcome bacterial resistance to amoxicillin. Together, these drugs form a prescription antibiotic product available in oral tablet, chewable tablet and thick liquid. It is available under brand name and generically.

Function

Amoxicillin with clavulanate potassium is prescribed for skin infections, urinary tract infections, middle ear infections, sinusitis, pneumonia and other conditions. It is effective against a wide range of bacteria, including some strains of streptococcus, Proteus mirabilis, Haemophilus influenzae, B. catarrhalis, Enterococcus faecalis, staphylococcus and Neisseria gonorrhoeae. It may demonstrate effectiveness against other organisms as well.

Side Effects

The most common side effect of amoxicillin and clavulanate potassium is diarrhea, explains the Merck Manual for Healthcare Professionals. Other common side effects include vaginal inflammation, vaginal yeast infection, nausea, heartburn, abdominal discomfort, intestinal gas, vomiting, skin rash, itchy hives, diaper rash and headache. A fungal infection that presents as one or more white patches in the throat or mouth may develop. These patches may be painful, making eating difficult. Severe allergic reactions are possible. Symptoms include hives and swelling of the face, mouth or throat. Throat swelling is a medical emergency that can cause breathing difficulties.

Contraindications

This combination medication should not be used by individuals allergic to any component of the product. Those allergic to penicillin should not take amoxicillin with clavulanate potassium. It is often contraindicated for people with severe kidney impairment and those requiring hemodialysis. The product should also be avoided by individuals who have suffered liver dysfunction or developed yellowing of the skin or eyes as a result of taking it in the past.

Precautions

Amoxicillin and clavulanate potassium should be used with caution by breastfeeding mothers as it does pass into breast milk. When taken for a long period of time, a fungal or severe bacterial infection may develop. This infection may not become apparent for up to two months after the course of medication is complete. Those with kidney problems may need to take a lighter dose or a different medication. It is not recommended for use by individuals suffering infectious mononucleosis, explains the Merck Manual for Healthcare Professionals. Some medications interact with this product; the prescribing physician should be aware of all medications the individual is currently taking.

Tips

Chewable tablets should be chewed, not swallowed whole. Oral tablets should be taken with a glass of water. The liquid suspension should be kept refrigerated and shaken well before use. Suspension doses should be measured carefully each time. If diarrhea develops during use, antidiarrheal medication should only be taken with the prescribing physician's approval, relates Drugs.com. Taking the medication at the beginning of a meal may reduce stomach upset.