Geodon is a prescription drug classified as an atypical anti-psychotic. It contains the generic medicine ziprasidone. Geodon is available as an oral capsule and an injection that is given into the muscle. According to the "2010 Lippincott's Nursing Drug Guide," Geodon oral capsules are given twice a day in doses of 20mg to 80mg. Intramuscular doses of 10mg to 20mg may be given, with a maximum dose of 40mg in a 24-hour period.
Effects in Schizophrenia
Oral Geodon treats some of the symptoms of schizophrenia. It is used to alleviate anger and withdrawal from social situations. Some individuals with schizophrenia are quiet and emotionless. Geodon is also beneficial for these symptoms. The drug may help those with a lack of motivation become more motivated to care for themselves, express themselves and engage in activities around them. Ziprasidone also helps lengthen the period of time between relapses of schizophrenic symptoms.
Effects in Agitation
Intramuscular Geodon is used to treat severe agitation, threatening behaviors, self-harming behaviors and other psychotic behaviors exhibited during acute schizophrenic episodes. It works rapidly to control behavior. The drug manufacturer recommends that intramuscular injections not be given to individuals already taking the oral preparation.
Effects in Bipolar Disorder
Oral Geodon is used to treat acute manic episodes and mixed episodes in bipolar disorder, according to the National Center for Biotechnology Information. Alleviated symptoms include extreme irritation, severe excitement and frenzied behavior. Ziprasidone is also given in combination with valproate or lithium for chronic treatment of bipolar disorder.
Adverse and Untoward Effects
A common side effect of Geodon is drowsiness, which can be significant. Caution must be used when driving or performing other critical tasks. Other common adverse effects include dizziness, nausea, heartburn, vomiting, constipation, restlessness, headache, vision changes, fever, loss of strength, respiratory tract infection and feeling sedated. Less common effects include weight gain, low or high blood pressure, dry mouth, abdominal pain, rash and heart rhythm changes. Extrapyramidal symptoms such as stiff muscles and uncontrolled body or facial movements can also occur from Geodon use. Other side effects are possible. Discuss the potential for adverse effects with the prescribing physician.
References
- “2010 Lippincott’s Nursing Drug Guide”; Amy M. Karch, R.N., M.S.; 2010
- National Center for Biotechnology Information: Ziprasidone
- Pfizer: Geodon Full Prescribing Information



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