Aggrenox belongs to a class of drugs known as antiplatelets. Platelets are important blood components that prevent bleeding from cuts and wounds by binding together to form blood clots. Antiplatelets inhibit blood clots by preventing platelets from sticking together. According to Aggrenox.com, Aggrenox is used to reduce the risk of stroke in patients with previous histories of mini-strokes or transient ischemic attacks. Aggrenox may cause several side effects.
Gastrointestinal Effects
According to Drugs.com, Aggrenox may cause common side effects such as heartburn, abdominal pain, nausea, vomiting and diarrhea. Aggrenox may also cause gastrointestinal bleeding and perforation. Aggrenox contains aspirin which increases the risk of gastrointestinal bleeding. The risk of gastrointestinal bleeding is higher when alcohol is consumed together with Aggrenox. Gastrointestinal bleeding may occur anytime during therapy and without obvious signs and symptoms. Patients should be aware of signs of gastrointestinal bleeding such as severe abdominal pain, coughing blood, coffee ground vomit and black tarry stool.
Nervous System Effects
Drugs.com states that Aggrenox may cause headaches, dizziness and weakness. Aggrenox may also cause bleeding in the brain leading to severe headaches, confusion, fainting and coma. Aggrenox contains aspirin which may cause Reye's syndrome in children with viral infections. Reye's syndrome is a serious condition that causes swelling in the brain and other body organs.
Liver and Kidney Failure
According to the National Institutes of Health, long-term use of Aggrenox and in high doses may cause liver and kidney failure. Signs of liver failure include pale colored stool, right upper abdominal pain, dark urine, itching and yellowing of the eyes and skin. Signs of kidney failure include decreased urination, swelling of the feet, sudden weight gain and wheezing and shortness of breath.
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