Side Effects of an MAO Inhibitor

Side Effects of an MAO Inhibitor
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A monoamine oxidase inhibitor, or MAO inhibitor, is a classification of drugs prescribed for the treatment of depressive disorder. MAO inhibitors work by blocking a chemical substance in the brain. It is very important to avoid certain foods, beverages and medicines while being treated with an MAO inhibitor, states Drugs.com. Patients should be counseled by their physicians regarding what should be avoided prior to starting treatment. There are some side effects associated with MAO inhibitor medications.

Dizziness, Lightheadedness and Fainting

Patients taking MAO inhibitors may experience dizziness, lightheadedness and fainting. These common side effects may be more likely to occur within the first several weeks of treatment. Dizziness, lightheadedness and fainting may be more likely to occur while changing positions, such as going from lying down to standing, states Drugs.com. Changing positions slowly may help lessen these effects. Patients should use caution while driving or completing tasks that may be dangerous until they know how their medication will affect them. If these side effects persist or become severe, reported them to a health care professional.

Changes in Mood and Behavior

MAO inhibitors may cause unwanted changes in mood and behavior. Symptoms can include agitation, irritability, worsening depression or suicidal thoughts. Patients should be closely monitored by their physicians for the first few months of treatment. Family members and caregivers should also be aware of these possible side effects.

Hypertensive Crisis

Some patients may develop an abnormally high blood pressure while taking an MAO inhibitor, called hypertensive crisis. According to MayoClinic.com, symptoms of hypertensive crisis include chest pain, enlarged pupils, fast or slow heartbeat, severe headache, increased sensitivity of eyes to light, increased sweating, nausea and vomiting, or a stiff or sore neck. Report these symptoms to a physician immediately.

Swelling

Patients taking an MAO inhibitor may experience lower-extremity swelling, also known as edema. This may be more likely to occur in the feet, ankles and legs. Eating a diet low in sodium, drinking additional water, and resting with the legs and feet elevated may help diminish swelling. In patients with cardiac disease, these symptoms may indicate a more serious problem. Bring any lower-extremity swelling to the attention of a physician.

References

Article reviewed by Christine Brncik Last updated on: Jul 12, 2010

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