Clonidine significantly relieves symptoms of opiate withdrawal by inhibiting brain noradrenergic activity. A study reported in JAMA found Clonidine to be 100 percent successful at reducing withdrawal symptoms.
References
- Opiate Withdrawal Using Clonidine; JAMA. 1980;243(4):343-346; Mark S. Gold, MD; A. Carter Pottash, MD; Donald R. Sweeney, MD, PhD; Herbert D. Kleber, MD; 1980
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