Hydrocodone-APAP, a narcotic analgesic containing acetaminophen and hydrocodone, is a semi-synthetic opioid drug derived from the natural opiates codeine and thebaine. The drug is available in tablet, capsule, syrup or solution form. It is used to treat moderate to severe post-operative pain, or may be prescribed for those suffering with chronic pain. Because it's an opiod drug, it should only be used as directed in order to avoid dependency.
Nausea
Stomach problems frequently occur when first starting a medication, and Hydrocodone-APAP is no exception. Some of the most frequently reported gastric effects of this drug, according to MedlinePlus, are nausea with or without vomiting, as well as a drop in appetite. These effects tend to resolve on their own as the body adjusts to the medication; however, the prescribing physician should be notified if these symptoms persist or become worrisome.
Drowsiness
Hydrocodone-APAP may cause drowsiness or fatigue, which likely will result in decreased alertness and reaction time. In addition to drowsiness, according to eMedTv.com, users may experience dizziness or feel lightheaded at times during the day. The combined effects of drowsiness and dizziness may increase the potential for accident or injury; therefore, it is advised not to drive or operate machinery until the extent of these effects is known.
Headache and Mood Changes
Another frequently observed drug effect that may occur in some patients is headaches. Headaches, depending on the degree of discomfort, may interfere with activities of daily living. Moreover, Drugs.com notes that other related effects, such as blurred vision or ringing in the ears, may also be experienced. Lying down periodically during the day as needed may help. Treatment with this medication also can produce changes in mood, such as unusual positive or sad mood states, as well as anxiety. The prescribing physician should be notified if any of these symptoms persist or increase in severity.
Constipation
This type of drug is notorious for slowing down gastric motility, which means that it may be difficult for users to have bowel movements. Thus, another frequent side effect, as reported by eMedTv.com, is severe constipation. This drug effect may be accompanied with abdominal pain or stomach cramping. Both stool softeners and laxatives may be required; also, the physician may make adjustments to the drug dosage.
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