Treatment of Peyronie's Disease

Overview

Peyronie's disease is a condition in which the penis becomes curved when erect. It is caused by the buildup of scar tissue (also known as plaque) on one side of the penis (typically on top or underneath). When the penis becomes erect, this scar tissue pulls the affected portion at an angle, leading to curvature of the penis and, in some cases, erectile dysfunction.

Step 1

Wait. Most doctors will recommend that you wait between 9 and 12 months before pursuing any further treatment to see whether the curvature gets better. Your physician may also monitor disease progression by measuring plaque amounts, erectile function and penile curvature.

Step 2

Take oral medications. Medicines, such as colchicine (inhibits collagen growth), Potaba, and vitamin E may help treat Peyronie's disease. These medications are generally only effective during the first year and a half, while the disease is still progressing.

Step 3

Receive injections in the affected area. Your doctor can inject drugs such as interferons, collagenase and verapamil into the penile plaque. These medications work by breaking down the scar tissue and allowing healthy tissue to be built. Usually multiple injections over a period of a few months are necessary for this to be effective.

Step 4

Get surgery. One surgical technique is called Nesbit plication and involves shortening the unaffected side of the penis, which reduces the curvature. This surgery does, however, shorten the length of the penis. Another option is to make several cuts in the plaque and then graft a vein over the incisions.

Step 5

Receive a prosthetic device. In some cases, your surgeon may elect to implant a device that will help straighten your penis and keep it rigid. This procedure is commonly used for men who are also experiencing erectile dysfunction.