Side Effects from Strattera

Side Effects from Strattera
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Strattera, or the generic product atomoxetine, is a norepinephrine reuptake inhibitor used for treatment of attention deficit/hyperactivity disorder. This prescription medication acts on norepinephrine, a chemical found in the brain. Strattera blocks the reabsorption of the chemical to bring the level back to normal. Strattera may produce side effects because of its activity in the body.

Dry Mouth, Nausea and Vomiting

Strattera may produce dry mouth in about 21 percent of patients. Drinking plenty of water or chewing gum may help with this side effect. Nausea may occur in up to 21 percent of users, while vomiting may occur in up to 11 percent. The medication is not affected by food, so the patient may take it with food to avoid these effects. The patient may begin to tolerate the drug with continued use and may see a decrease in these side effects.

Abdominal Pain and Decreased Appetite

Merck.com reports that about 7 to 18 percent of individuals using Strattera may develop abdominal pain. If abdominal pain becomes severe, the patient should receive medical care. The medication may also cause a decreased appetite. Gastrointestinal side effects may contribute to the decrease in appetite. If the patient loses a lot of weight without trying, he should inform a physician.

Headache

A common side effect that patients may experience while on Strattera is headache. Headache may occur in up to 19 percent of patients. This is an adverse effect that becomes tolerable with time. A pain reliever may be used to alleviate headaches. If headaches continue or become worse, the patient should contact a physician.

Dizziness and Drowsiness

Dizziness and drowsiness are common side effects that may appear during the use of Strattera. Dizziness may occur in about 5 percent of patients and drowsiness may occur in about 11 percent of patients, according to Merck.com. Fatigue and sluggishness may also be present in about 6 to 9 percent of users. Patients should be warned to avoid driving or operating heavy machinery. Patients should also use caution when climbing stairs or performing unsafe activities. When the patient learns the effects of the drug, she can continue these activities.

Insomnia

Insomnia, or difficulty sleeping, may occur with this medication. Up to 15 percent of users experience insomnia. About 3 percent of users experience sleep disturbances, such as abnormal dreams. If these adverse effects heavily affect the patient, he should speak with a physician for a dose reduction or discontinuation. Other medications may be better-tolerated by the patient.

Liver Toxicity

Strattera has a black box warning that states that there is a potential for severe liver injury, according to "Pharmacotherapy: A Pathophysiologic Approach." Patients with liver disease should use the medication with caution. Liver toxicity is rare, but if the patient develops symptoms, she should stop the drug and not restart it. Signs and symptoms include itchiness, yellowing of the skin and eyes, and such flu-like symptoms as fever, headache and muscle aches. Although this side effect is rare, it is serious and the patient should immediately call a physician if she experiences any of these symptoms.

References

  • Merck.com: Atomoxetine
  • "Pharmacotherapy: A Pathophysiologic Approach"; Joseph T. Dipiro, Robert L. Talbert, et al.; 2008

Article reviewed by Eric Lochridge Last updated on: Jul 19, 2010

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