Aviane 28 is a medication in a class of drugs known as combination oral contraceptives. Aviane works to prevent pregnancy by inhibiting ovulation and altering the uterine lining and consistency of cervical mucous. Women who have a history of cardiovascular disease, diabetes, breast cancer, stroke, migraine with aura, and liver disease should not take oral contraceptives, says Drugs.com. Oral contraceptives offer protection against pregnancy but will not protect women from sexually transmitted infections or HIV. There are some side effects associated with oral contraceptives that women should be aware of prior to starting treatment with Aviane 28.
Irregular Bleeding
Women taking Aviane 28 may experience irregular bleeding, including breakthrough bleeding and spotting. These side effects may diminish after a few months of treatment as the body adjusts to the hormones in Aviane. Taking the pill at the same time every day and not missing any pills may help to reduce the risk of these side effects. Irregular bleeding that worsens or persists should be brought to the attention of a gynecologist.
Breast Changes
Aviane 28 may cause breast changes. Symptoms can include breast tenderness, pain, or swelling, says Drugs.com. These side effects may diminish as the body adjusts to this medication. Women should continue self breast examination and mammography as recommended by their physician. Any changes in breast tissue or development of a breast lump should be brought to the attention of a physician immediately.
Stomach Discomfort
Oral contraceptives such as Aviane 28 may cause stomach discomfort in some users. Symptoms can include stomach cramps, nausea, vomiting, and bloating. Making small dietary changes such as eating smaller meals more frequently and avoiding spicy and fatty foods may help alleviate stomach discomfort. Nausea and vomiting may be helped by taking the pill in the evening or at bedtime, explains Planned Parenthood.
Skin Changes
Some women may experience skin changes while taking Aviane 28. According to Drugs.com, freckles or darkening of facial skin may occur. These side effects may be temporary or last for a long period of time. Patients who experience severe skin changes may want to contact a dermatologist for further evaluation.



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