Pristiq, the brand name of the medication desvenlafazine, is an antidepressant used to treat major depressive disorder. It works by affecting the chemicals in the brain responsible for mood regulation. Although this medication can be an effective treatment for depression, it is not for everyone. Patients with depression should talk to their doctor about the advantages and disadvantages of the medication before taking Pristiq.
Step 1
See a doctor. Pristiq is only available by prescription, so you will have to make a trip to the doctor to obtain the medication. Talk to your doctor about your previous medical history, current medications and provide detailed information about your depression symptoms at the visit.
Step 2
Begin taking the medication. The typical dose is 50 mg once a day, according to Pristiq prescribing information, but always follow the specific dosing instructions from your doctor. Swallow each Pristiq tablet whole. Crushing, dividing, chewing or dissolving the tablet may reduce its effectiveness. Pristiq can be taken with or without food.
Step 3
Monitor your body for side effects. Common side effects include nausea, dizziness, insomnia, constipation, decreased appetite, anxiety, male sexual dysfunction, drowsiness and increase perspiration. Always call a doctor if you experience any side effect that seems unusual or is particularly unpleasant.
Step 4
Keep follow-up appointments with a doctor. It is important to continue to see a doctor while taking Pristiq to reduce the risk of serious medical complications.
Step 5
Gradually reduce the dosage. Once a doctor has determined that you no longer need Pristiq or you need to switch to a new medication, begin gradually lowering the amount of Pristiq you take each week. Stopping Pristiq too suddenly may cause serious withdrawal symptoms.
Tips and Warnings
- Although Pristiq alone may help to reduce the symptoms of your depression, counseling often provides additional benefits and may make you feel even better.
- Some people taking Pristiq experience serious side effects that may indicate a dangerous medical condition. These include seizure, feeling faint, tremors, unusual heartbeats, confusion, high fever, rigid muscles, agitation, loss of coordination or balance, diarrhea, nausea, vomiting, overactive reflexes, hallucinations, vision changes, eye pain, coughing up blood, easy bruising or bleeding, blood in urine or stools, chest tightness and trouble bleeding, according to Drugs.com. If you experience any of these side effects, seek immediate medical attention.


