Mast cell stabilizers are a class of medication that is commonly used for the treatment of allergies. One of the more commonly prescribed mast cell stabilizers is cromolyn, though other forms, such as pemirolast, can be obtained in the form of eyedrops. These compounds are generally safe but can produce certain side effects, which are usually mild.
Nasal
Cromolyn, when taken as a nasal solution, can cause nasal irritation, stinging, congestion and sneezing, RxList.com notes. Mast cell stabilizers in eye drops can cause inflammation of the nasal passages and sinus congestion. The side effects of pemirolast, according to RxList, are often very mild. Patients also report experiencing postnasal drip, in which mucus from the nose travels down to the throat and into the lungs. This can lead to a sore throat.
Unpleasant Taste
An unpleasant taste in the mouth after the use of cromolyn is a commonly reported side effect, Drugs.com notes.
Respiratory Symptoms
Patients taking cromolyn may also experience some respiratory side effects. Common side effects from the inhalable versions of cromolyn include wheezing and a cough, Drugs.com explains. Patients may also experience a feeling of tightness in the lungs. Irritation of the voicebox, resulting in hoarseness, has also been reported.
Eye
The use of mast cell stabilizers in the form of eyedrops can lead to tearing, itching and redness in the eyes.
Allergic
Mast cell stabilizers can also generate an allergic reaction in some patients. A mild allergic reaction can result in a rash with hives appearing anywhere on the body. Stronger allergic reactions can cause swelling of the lips, tongue, fingers and face, according to eMedTV. Anaphylaxis, which is a severe allergic reaction, can result in trouble breathing and swallowing as well as tightness of the chest.



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