Itching has many possible causes. It most often results from disorders within the skin but can also result from underlying conditions within the body, according to the journal American Family Physician. Sometimes, itchy skin free is free from a rash or other symptoms, such as blisters and bumps. Causes of itching without a rash can be harmless, such as dry skin, or it can signify a serious underlying disorder, such as liver or kidney disease, lymphoma or leukemia.
Dry Skin
Itching associated with dry skin, or xerosis, commonly occurs during the winter in cold climates, due to low humidity in the air. Older adults are affected most often. Dry skin can cause intense itching, the journal American Family Physician says. Itching is usually most severe in the lower legs. The flank, waist, back and abdomen are also commonly involved. Scratching dry skin can result in an appearance similar to cracked porcelain. The American Academy of Family Physicians, or AAFP, recommends applying a moisturizer three times per day and says ointments, or oils, are best. Mild soaps should be used, and oatmeal baths may be soothing. Itching that is not resolved after two weeks should be evaluated by a physician, the AAFP says.
Hodgkin's Lymphoma
Hodgkin's lymphoma, or Hodgkin's disease, is a cancer of the lymph tissue. Lymph tissue is found in the lymph nodes, bone marrow, spleen and liver, according to MedlinePlus. The first sign is usually a firm, painlessly enlarged lymph node. Itching all over the body is also a common symptom. Soaking night sweats, chest pain, coughing, fever and chills, unexplained weight loss and fatigue can also occur. Treatment depends on the stage of the disease when discovered and may include chemotherapy, radiation or a bone marrow transplant.
Cholestasis
Cholestasis, a blockage of the ducts that drain bile from the liver, is a condition that can result from liver disease or pregnancy. Bile is the fluid excreted by the liver that digests fats in the small intestine. Intense skin itching without a rash occurs with cholestasis, due to the buildup of bile salts and bilirubin in the skin. Cholestasis is the cause of some of the most severe itching, according to American Family Physician. The hands and feet are most commonly affected, and itching typically worsens at night. Cholestasis can also result from medications such as birth control pills, some antipsychotic drugs and Augmentin, an antibiotic.
