Mirapex, known by the generic name pramipexole, is a drug that is used to treat restless leg syndrome (RLS). RLS is a condition that causes burning, crawling and creeping sensations within the legs. Mirapex can help to control these sensations, but there are several possible side effects when taking the drug. Knowing the side effects of Mirapex for restless legs can help people with RLS to determine if they should start treatment or not.
Nervous System
Several nervous system side effects have been reported as a result of using Mirapex for restless leg syndrome. According to the National Institutes of Health, headache and drowsiness are two of the most common nervous system side effects. The Mirapex consumer information sheet at Drugs.com indicates that dizziness, hallucinations and sleep problems have also been reported. In clinical trials, nervous system side effects were the most common reason for discontinuing therapy with Mirapex.
Digestive System
The National Institutes of Health cites several digestive system side effects that can occur when this drug is used to treat restless leg syndrome. The most common digestive side effects are nausea, dry mouth, diarrhea and constipation. Taking food with Mirapex may help lessen the severity of these side effects. The Drugs.com information sheet on Mirapex lists anorexia and difficulty swallowing as additional side effects that can impact the digestive system.
Urinary System
Drugs.com lists several urinary system side effects of Mirapex. These side effects include urinary frequency, urinary incontinence and urinary tract infection (UTI). In men, impotence has also been reported as a side effect of using this drug. Urinary side effects are uncommon and should be reported to a medical professional. These side effects can indicate a need to reduce the dosage of Mirapex or to replace it with another drug.
Psychiatric Effects
Boehringer Ingelheim, the manufacturer of Mirapex, warns that the drug may affect mood and behavior. This drug may cause users to develop compulsive behaviors or an inability to control their impulses. This may show up as new or increased sexual urges, compulsive shopping, a new or increased urge to gamble or compulsive eating. Hallucinations have also been reported by people taking Mirapex. These side effects should be reported to a physician immediately.
General Effects
Mirapex can cause several side effects that are not specific to one body system. Instead, they affect the entire body. The National Institutes of Health lists fatigue as the most common general side effect. Drugs.com also lists swelling, a general feeling of malaise and physical weakness as possible side effects of Mirapex.



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