Asacol is a prescription anti-inflammatory medication for ulcerative colitis, or inflammation of the large intestines and rectum. Asacol is normally prescribed for mild to moderate cases of ulcerative colitis. Asacol comes in pill form in 400 mg doses, with an adult dose of two tablets up to three times daily.
Mesalamine
Mesalamine, chemically known as 5-amino-2-hydroxybenzoic acid, is an anti-inflammatory medication. According to Drugs.com, mesalamine works inside the intestines to reduce inflammation and other symptoms of ulcerative colitis. Mesalamine is used to reduce the frequency of ulcerative colitis flare-ups. It is also sometimes prescribed to individuals suffering from Crohn's disease.
The mesalamine in Asacol is coated with a special layer to ensure that it does not dissolve prior to entering the intestines. Once within the intestines, mesalamine acts as a topical anti-inflammatory.
Inactive Ingredients
Inactive ingredients called carrier agents are added to Asacol to aid in digestion and assimilation; these include magnesium stearate, povidone and sodium starch glycolate. They carry the active ingredient, mesalamine, through the body.
Other ingredients are used to make the tablet and ensure proper delivery method of the active ingredient. Colloidal silicon dioxide is used as a thickening agent, while dibutyl phthalate and methacrylic acid copolymer B are used to bring all the ingredients together to make a tablet.
Polyethylene glycol is added because it allows for slow digestion to ensure proper delivery in the intestines.
Flavoring and Color
Talc, edible black ink, iron oxide red and iron oxide yellow are added to Asacol to provide color. Although listed as inactive ingredients, allergic reactions to these substances may still occur, so Asacol users should consult with a physician to discuss any concerns about these inactive ingredients.
References
- Drugs.com: Asacol
- RxList: Asacol
- Merriam-Webster OnLine: Povidone
- "Handbook of Fillers, Extenders, and Diluetants"; Michael Ash, Irene Ash; 2007
- NBent: Sodium Starch Glycolate



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