The term, cellulitis refers to a diffuse and especially subcutaneous inflammation of the dermis, the sensitive vascular inner mesodermic layer of the skin. The species of staphylococcus and streptococcus bacteria are the most common causative organisms of cellulitis. With cellulitis, the skin becomes hot and swollen and may look slightly pitted. Streptococci spread rapidly in the skin because they secrete proteinase, an enzyme which blocks the ability of the tissue to confine the infection. They enter the nearby lymph nodes, and in most serious cases, into the bloodstream. Cellulitis is potentially life-threatening and has a mortality rate, if untreated.
Cefepime
Cefepime is a fourth-generation cephalosporin antibiotic produced by Cephalosporium acremonium, an imperfect fungus species, which can be administered intravenously, or by suppository. This drug is highly resistant to a broad spectrum of beta-lactamases, enzymes found especially in staphylococcal bacteria, and is active against a wide range of both gram-positive and gram-negative organisms. According to a 2010 study conducted by the National Cancer Institute, cefipime inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
Dicloxacillin
Dicloxacillin is a bactericidal antibiotic drug of penicillin group. It is used to treat bacterial infections caused especially by penicillinase-producing organisms such as Staphylococcus aureus. It works to inhibit the synthesis of bacterial cells walls and fight the infection. Dicloxacillin comes in the form of capsules and oral liquid. This medicine is to be taken by mouth four times a day. Like other beta-lactam antibiotics, dicloxcillin cause side effects; these include stomach upset, diarrhea, vomiting and mild skin rash.
Cephalexin
Cephalexin is a cephalosporin antibiotic, a class of beta-lactam antibiotic originally derived from Acremonium bacteria, prescribed to treat bacterial infections in the body. This bactericidal is active against rapidly growing organisms forming cell walls. Cephalexin arrests mucopeptide synthesis in the bacterial cell walls by binding to one or more penicillin-binding proteins. This results in the rupturing of the bacterial cell wall and causes cell lysis.
