Creatinine is a byproduct of a substance called creatine, which is in our muscles and plays a critical role in bodily functions--it is removed from the body solely by the kidneys. Creatinine is the waste that develops from the metabolism of the muscle. When levels of creatinine become too high it can be dangerous and can cause the kidney's to shut down. A laboratory test called serum creatinine or a urinalysis will help to show how the kidneys are functioning.
Diabetes
High creatinine levels can be caused by diabetes. Diabetes often damages the kidneys, especially when the disease is not controlled and blood sugar levels are not kept within a normal range. According to the Mayo Clinic, diabetes can cause a breakdown of fat which causes a toxic acid called ketones to build up in the kidney. If left untreated, this buildup of ketones can cause serious kidney damage and this can lead to high creatinine levels. Diabetes should be respected; it is important to monitor your blood sugar levels as your physician prescribes. Any changes in the health of your kidneys or diabetes should be immediately reported to your physician.
Chronic Kidney Failure
Damage to your kidneys can be a cause of chronic kidney failure. According to the Mayo Clinic, chronic kidney failure occurs when there is a gradual loss of kidney function. This can cause a buildup of toxins and waste in the body and lead to high creatinine levels. According to the Mayo Clinic, this chronic kidney failure can be caused by a variety of reasons including high blood pressure, enlarged prostate, lupus, kidney cancer and scleroderma. Kidney failure is a life-threatening medical condition and requires immediate medical attention.
Urinary Tract Blockage
A blocked urinary tract can lead to a buildup of creatinine levels, and this can show as high levels in lab results. According to the University of Maryland Medical Center, urinary tract blockages can occur because of bladder cancer, kidney stones, blood clots, neurogenic bladder and various other reasons. This can be a serious medical condition and should be immediately checked out by a physician. It can cause pain, discomfort and even lead to hospitalization.
