Add magnesium glycinate to your diet if you are one of the 50 percent to 75 percent of the population who are said to be magnesium-deficient. And if you are a trained athlete, you are almost certainly magnesium-deficient, according to nutrition expert and strength trainer Charles Poliquin and sports injury specialist Dr. Stuart Yoss, practicing at the Poliquin Performance Center in Chicago. However, Mayo Clinic physicians reported in 2009 that a well-balanced diet makes magnesium deficiency rare, except in disease.
Depression
George Eby, executive director of the George Eby Research Institute in Texas, reported in a 2006 edition of the journal "Medical Hypothesis" that a special regimen of magnesium glycinate administration produced a rapid and significant decrease in the symptoms of patients diagnosed with major depression. Eby suggests that magnesium-deficient diets should be fortified by replacing magnesium lost during grain processing and by increasing overly purified drinking water's magnesium to pre-20th century levels. Major depression symptoms include severe irritability and a tendency to suicidal ideation and attempts. Eby recommend further research and does not recommend self-administration of this remedy; inappropriate treatment of major depression is dangerous. Direct medical supervision must determine your therapy.
Glycine, the agent combined with magnesium in this preparation, is an amino acid widely distributed throughout your brain and spinal cord that's known to act as a neurotransmitter, producing both inhibitory and excitatory effects. Dr. Steven Paul, a neurotransmitter researcher, reported in a 2000 edition of the "Journal of the American College of Neuropsychopharmacology" that many cognitive, motor and emotional abnormalities can be traced to problems with glycine intake and metabolism. The benefits of magnesium glycinate in treatment for depression have not been clearly attributed to either the magnesium or the glycine, or their combination. Patients treating depression should not attempt to use this compound without medical supervision.
Vomiting and Diarrhea
Mayo Clinic physicians indicated in a 2009 report that a well-balanced diet supplies the recommended amount of magnesium for most people. However, deficiencies can occur if you experience prolonged and severe diarrhea or vomiting. These can deplete gastrointestinal and blood stores of magnesium. Symptoms include muscle weakness, irregular heartbeat and irritability. Magnesium compounds, including magnesium glycinate, are administered under medical supervision to treat these deficiencies.
Biochemistry
The U.S. National Institutes of Health Office of Dietary Supplements reported in 2010 that more than 300 biochemical reactions in your body rely on magnesium for proper activity. The body systems supported by magnesium include normal muscle and nerve functions, heart rhythm regularity, immunities and bone strength. Fifty percent of your body's total magnesium is part of your bone structure. Blood sugar, blood pressure, energy metabolism and protein synthesis also depend on magnesium. Many magnesium compounds, including magnesium glycinate, are well tolerated and provide bio-available magnesium to support all of this vital biochemistry within your body.
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